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y set to human . Trideutero-acetylation at lysines, carbamidomethylation of cysteine and methionine oxidation to methioninesulfoxide had been set as fixed modifications. Variable modifications included 13C2-acetylation, d3-acetylation, acetylation and pyroglutamate formation of N-terminal glutamine. Endoproteinase ArgC/P was set as enzyme permitting no missed cleavages. The mass tolerance around
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